Lipopolysaccharide-binding and neutralizing peptides
作者： Adolf Hoess , Robert C. Liddington
DOI:
关键词: Heparin 、 DNA 、 Bacterial sepsis 、 Microbiology 、 Recombinant DNA 、 Lipopolysaccharide binding 、 Lipopolysaccharide 、 Biology
摘要: The present invention relates to substances which bind with high affinity endotoxin (lipopolysaccharide [LPS]), and are useful for the prevention or treatment of, example, Gram-negative Gram-positive bacterial sepsis, of fungal infections as well neutralizing effects associated heparin. LPS-binding peptides comprising an domain. In addition, DNA sequences encoding said peptides, recombinant microorganisms containing DNA, pharmaceutical compositions invention, diagnostic kits. also encompasses methods detection removal LPS from solutions.
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