摘要: Le but de ce chapitre est presenter maniere succincte les principes essentiels la biostatistique en recherche clinique. L’approche adoptee dans deliberement pragmatique et n’a pour ambition que a l’investigateur choix effectuer lors planification des essais cliniques cancerologie. On mettra donc l’accent sur plans experimentaux (experimental designs) qui sous-tendent ces essais. lecteur interesse par un expose methodologique plus approfondi pourra soit consulter l’excellent livre publie recemment Piantadosi general [1] references specifiques cancerologie [2]–[6], encore generales methodes statistiques clinique [7].
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