作者: Cay M. Kielty , Jonathan Ghosh , Michael G. Walker , Nadeem Khwaja , Anastassi Halka
DOI:
关键词: Extracellular 、 Transforming growth factor 、 Function (biology) 、 Neuroscience 、 Cell type 、 Biology 、 Endocrinology 、 Internal medicine
摘要: The transforming growth factor h (TGFh) family of cytokines exert pleiotropic effects upon a wide variety cell types. TGFh1 has been demonstrated to be fundamental importance in the development, physiology and pathology vascular system. As role these processes becomes clearer, influencing its activity for therapeutic benefit is now beginning investigated. This review presents an overview vasculature. cellular extracellular biology TGFh first addressed, followed by function during atherogenesis, hypertension, vessel injury. D 2005 Elsevier Inc. All rights reserved.