Induction of hepatic cytochrome P450 enzymes: methods, mechanisms, recommendations, and in vitro-in vivo correlations.
作者： N. J. Hewitt , E. L. Lecluyse , S. S. Ferguson
DOI: 10.1080/00498250701534893
关键词: In Vitro Techniques 、 Enzyme 、 In vitro 、 Cytochrome P450 、 Biology 、 Transporter 、 Pharmacology 、 Enzyme inducer 、 Pharmacokinetics 、 Nuclear receptor
摘要: … , species differences in nuclear receptor activation make the prediction of cytochrome P450 (CYP… Thus, in vitro human-relevant model systems are increasingly used to evaluate enzyme …
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