A Growth Curve Analysis of the Course of Dysthymic Disorder: The Effects of Chronic Stress and Moderation by Adverse Parent-Child Relationships and Family History.

摘要: Using mixed effects models, the authors examined of chronic stress, adverse parent-child relationships, and family history on 7.5-year course dysthymic disorder. Participants included 97 outpatients with early-onset dysthymia who were assessed semistructured interviews at baseline 3 additional times 30-month intervals for 7.5 years. Results indicated that higher levels stress 6 months prior to each follow-up predicted greater depression severity follow-up, controlling start assessment. In addition, relationships disorder moderated this association. For patients poorer was associated increased whereas a familial loading less responsive over time.