Molecules that Promote or Enhance Reprogramming of Somatic Cells to Induced Pluripotent Stem Cells
作者： Bo Feng , Jia-Hui Ng , Jian-Chien Dominic Heng , Huck-Hui Ng
DOI: 10.1016/J.STEM.2009.03.005
关键词: Induced stem cells 、 Biology 、 Reprogramming 、 Somatic cell 、 Transduction (genetics) 、 Cell potency 、 Transcription factor 、 Induced pluripotent stem cell 、 Genetics 、 Cell biology 、 Cell signaling
摘要: Reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) can be achieved by viral-mediated transduction of defined transcription factors. Moving toward the eventual goal of clinical application, it is necessary to overcome limitations such as low reprogramming efficiency and genomic alterations due to viral integration. Here, we review recent progress made in the usage of genetic factors, chemical inhibitors, and signaling molecules that can either replace core reprogramming factors or enhance reprogramming …
elsevier.com
sci-hub.se 参考文章(97)
Howard J. Jacob, Anne E. Kwitek, Rat genetics: attaching physiology and pharmacology to the genome. Nature Reviews Genetics. ,vol. 3, pp. 33- 42 ,(2002) , 10.1038/NRG702
Sarah Eminli, Jochen Utikal, Katrin Arnold, Rudolf Jaenisch, Konrad Hochedlinger, None, Reprogramming of Neural Progenitor Cells into Induced Pluripotent Stem Cells in the Absence of Exogenous Sox2 Expression Stem Cells. ,vol. 26, pp. 2467- 2474 ,(2008) , 10.1634/STEMCELLS.2008-0317
Jonghwan Kim, Jianlin Chu, Xiaohua Shen, Jianlong Wang, Stuart H. Orkin, An extended transcriptional network for pluripotency of embryonic stem cells Cell. ,vol. 132, pp. 1049- 1061 ,(2008) , 10.1016/J.CELL.2008.02.039
Huafeng Xie, Min Ye, Ru Feng, Thomas Graf, Stepwise Reprogramming of B Cells into Macrophages Cell. ,vol. 117, pp. 663- 676 ,(2004) , 10.1016/S0092-8674(04)00419-2
Tarjei S. Mikkelsen, Jacob Hanna, Xiaolan Zhang, Manching Ku, Marius Wernig, Patrick Schorderet, Bradley E. Bernstein, Rudolf Jaenisch, Eric S. Lander, Alexander Meissner, Dissecting direct reprogramming through integrative genomic analysis Nature. ,vol. 454, pp. 49- 55 ,(2008) , 10.1038/NATURE07056
Natalia Ivanova, Radu Dobrin, Rong Lu, Iulia Kotenko, John Levorse, Christina DeCoste, Xenia Schafer, Yi Lun, Ihor R. Lemischka, Dissecting self-renewal in stem cells with RNA interference Nature. ,vol. 442, pp. 533- 538 ,(2006) , 10.1038/NATURE04915
Masato Nakagawa, Michiyo Koyanagi, Koji Tanabe, Kazutoshi Takahashi, Tomoko Ichisaka, Takashi Aoi, Keisuke Okita, Yuji Mochiduki, Nanako Takizawa, Shinya Yamanaka, Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts Nature Biotechnology. ,vol. 26, pp. 101- 106 ,(2008) , 10.1038/NBT1374
Eran Meshorer, Dhananjay Yellajoshula, Eric George, Peter J. Scambler, David T. Brown, Tom Misteli, Hyperdynamic Plasticity of Chromatin Proteins in Pluripotent Embryonic Stem Cells Developmental Cell. ,vol. 10, pp. 105- 116 ,(2006) , 10.1016/J.DEVCEL.2005.10.017
Jing Liao, Chun Cui, Siye Chen, Jiangtao Ren, Jijun Chen, Yuan Gao, Hui Li, Nannan Jia, Lu Cheng, Huasheng Xiao, Lei Xiao, Generation of Induced Pluripotent Stem Cell Lines from Adult Rat Cells Cell Stem Cell. ,vol. 4, pp. 11- 15 ,(2009) , 10.1016/J.STEM.2008.11.013
Trond Aasen, Angel Raya, Maria J Barrero, Elena Garreta, Antonella Consiglio, Federico Gonzalez, Rita Vassena, Josipa Bilić, Vladimir Pekarik, Gustavo Tiscornia, Michael Edel, Stéphanie Boué, Juan Carlos Izpisúa Belmonte, Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes. Nature Biotechnology. ,vol. 26, pp. 1276- 1284 ,(2008) , 10.1038/NBT.1503