Anti-diabetic potential of plant alkaloids: Revisiting current findings and future perspectives

作者: Hassan Rasouli , Reza Yarani , Flemming Pociot , Jelena Popović-Djordjević

DOI: 10.1016/J.PHRS.2020.104723

关键词: Biological activityDrug developmentGlucose homeostasisMedicineMedicinal plantsDiabetes mellitusIn vivoIn vitroPharmacologyInsulin resistance

摘要: … The α-A inhibitors can be widely obtained from higher plants, … Recently, isoquinoline and bis-isoquinoline alkaloids backbones … structure of these compounds is critical for potential drug …

参考文章(141)
Véronique Roig-Zamboni, Beatrice Cobucci-Ponzano, Roberta Iacono, Maria Carmina Ferrara, Stanley Germany, Yves Bourne, Giancarlo Parenti, Marco Moracci, Gerlind Sulzenbacher, Structure of human lysosomal acid α-glucosidase-a guide for the treatment of Pompe disease. Nature Communications. ,vol. 8, pp. 1111- 1111 ,(2017) , 10.1038/S41467-017-01263-3
Eun Ju Bae, Sirtuin 6, a possible therapeutic target for type 2 diabetes Archives of Pharmacal Research. ,vol. 40, pp. 1380- 1389 ,(2017) , 10.1007/S12272-017-0989-8
Stefania Bellini, Federica Barutta, Raffaella Mastrocola, Luigi Imperatore, Graziella Bruno, Gabriella Gruden, Heat Shock Proteins in Vascular Diabetic Complications: Review and Future Perspective International Journal of Molecular Sciences. ,vol. 18, pp. 2709- ,(2017) , 10.3390/IJMS18122709
Jelena B. Popovic-Djordjevic, Ivana I. Jevtic, Tatjana P. Stanojkovic, Antidiabetics: Structural Diversity of Molecules with a Common Aim. Current Medicinal Chemistry. ,vol. 25, pp. 2140- 2165 ,(2017) , 10.2174/0929867325666171205145309
Mohammed Ajebli, Mohamed Eddouks, Buxus sempervirens L Improves Streptozotocin-induced Diabetes Mellitus in Rats. Cardiovascular and Hematological Disorders - Drug Targets. ,vol. 17, pp. 142- 152 ,(2017) , 10.2174/1871529X17666170918140817
Min-Hsiung Pan, Jia-Ching Wu, Chi-Tang Ho, Ching-Shu Lai, Antiobesity molecular mechanisms of action: Resveratrol and pterostilbene Biofactors. ,vol. 44, pp. 50- 60 ,(2018) , 10.1002/BIOF.1409
Xiao Zheng, Fei Wu, Xiao Lin, Lan Shen, Yi Feng, Developments in drug delivery of bioactive alkaloids derived from traditional Chinese medicine Drug Delivery. ,vol. 25, pp. 398- 416 ,(2018) , 10.1080/10717544.2018.1431980
Leire Méndez-Giménez, Silvia Ezquerro, Inês V. da Silva, Graça Soveral, Gema Frühbeck, Amaia Rodríguez, Pancreatic Aquaporin-7: A Novel Target for Anti-diabetic Drugs? Frontiers in Chemistry. ,vol. 6, pp. 99- 99 ,(2018) , 10.3389/FCHEM.2018.00099
Nagaraju Kerru, Ashona Singh-Pillay, Paul Awolade, Parvesh Singh, Current anti-diabetic agents and their molecular targets: A review. European Journal of Medicinal Chemistry. ,vol. 152, pp. 436- 488 ,(2018) , 10.1016/J.EJMECH.2018.04.061
Sue Edwards, Inga Hedberg, Mesfin Tadese, Flora of Ethiopia and Eritrea vol. 2, Part 2: canellaceae to euphorbiaceae AAU. ,(1995)