Synthesis of 1,3-disubstituted cyclohexenes from dienylethers via sequential hydrozirconation/deoxygenative cyclisation.
作者： Amandine Payet , Benjamin Blondeau , Jean-Bernard Behr , Jean-Luc Vasse
DOI: 10.1039/C8OB02925C
关键词: Cyclohexenes 、 Allylic rearrangement 、 Chemistry 、 Carbocation 、 Electrophile 、 Stereochemistry
摘要: Access to 1,3-disubstituted cyclohexenes from zirconocenes containing a latent electrophilic allylic fragment is described. Requiring specific conformation, 6-endo-trig cyclisation based on the TMSOTf-mediated generation of stabilized carbocation.
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