Photopolymerization of Poly(Ethylene Glycol) Diacrylate on Eosin-Functionalized Surfaces

摘要: We describe a new method that allows photopolymerization of hydrogels to occur on surfaces functionalized with eosin. In this work, glass and silicon were derivatized eosin was carried out using visible light (514 nm). This mild condition may have advantages over methods use ultraviolet (UV) (e.g., for encapsulation cells proteins, in drug screening, or biosensing applications). The hydrogel formed the modified surface is remarkably stable an extended period time. resultant hydrated more than 18 months without suffering delamination from substrate surface. strongly suggests covalent attachment Contact angle titration measurements X-ray photoelectron spectroscopy analysis before after irradiation presence triethanolamine suggest radical responsible gel onto 2-D patterning hydrogels, which demonstrated here microcontact printing technique. However, noncontact photolithography could be used form similar patterns by directing through mask. can easily implemented arrays fluorophores proteins situ.