作者: Maria Guido , Alessandra Mangia , Gavino Faa
DOI: 10.1016/S1590-8658(11)60589-6
关键词: Pathology 、 Liver biopsy 、 Hepatitis C 、 Internal medicine 、 Biopsy 、 Clinical significance 、 Disease 、 Medicine 、 Viral hepatitis 、 Hepatitis B 、 Grading (tumors)
摘要: In chronic viral hepatitis, the role of liver biopsy as a diagnostic test has seen decline, paralleled by its increasing importance for prognostic purposes. Nowadays, main indication in hepatitis is to assess severity disease, terms both necro-inflammation (grade) and fibrosis (stage), which important prognosis therapeutic management. Several scoring systems have been proposed grading staging there no general consensus on best system be used daily practice. All their drawbacks all may affected sampling observer variability. Whatever used, histological score reductive approach since damage complex biological process. Thus, are not intended replace detailed, descriptive, pathology report. fact, lesions other than those scored clinical relevance should assessed reported. This paper aims provide systematic interpretation biopsies obtained cases with hope helping pathologists