Cancer and venous thromboembolism

作者: Paolo Prandoni , Anna Falanga , Andrea Piccioli

DOI: 10.1016/S1470-2045(05)70207-2

关键词: ThrombosisVenous thromboembolismHormone therapyAdjuvantMedicineChemotherapyCancerIntensive care medicineHeparinOccult

摘要: Summary Venous thromboembolism occurs commonly in patients with cancer. The pathogenetic mechanisms of thrombosis involve a complex interaction between tumour cells, the haemostatic system, and characteristics patient. Among risk factors for are long-term immobilisation, especially hospital, surgery, chemotherapy or without adjuvant hormone therapy. Although prophylaxis treatment cancer draw on agents that used those cancer, there many special features make use these drugs more challenging. Low-molecular-weight heparins cornerstone venous These have potential to increase survival, at least favourable outlook. About 10% idiopathic an underlying malignant disorder can be detected by extensive diagnostic investigation. However, issue whether screening occult disease ultimately improves prognosis survival remains resolved.

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