Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays.

作者: Jason M Johnson , John Castle , Philip Garrett-Engele , Zhengyan Kan , Patrick M Loerch

DOI: 10.1126/SCIENCE.1090100

关键词: RNA splicingGeneticsDNA microarrayHuman genomeBiologyAlternative splicingComputational biologyExonic splicing enhancerGeneGenomeExon

摘要: … exon-exon junction in more than 10,000 multi-exon human … 74% of human multi-exon genes are alternatively spliced. … of the human proteome and at least half of human genes are …

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