Ewing’s Sarcoma: Current Concepts in Chemotherapy and Surgical Control

摘要: Ewing sarcoma is a relatively rare tumor of childhood and constitutes 3% all pediatric malignancies. It pathologically malignant round cell tumor, CD99 positive on immunohistochemical staining characterized by unique translocation, t(11;22). The most common presenting symptoms are persistent pain swelling. Imaging primary site biopsy essential for confirmation diagnosis staging work-up includes bone marrow biopsy, scan CT chest. A comprehensive multidisciplinary approach incorporating multiagent chemotherapy along with surgery or radiation therapy the standard care. Outcome patients localized disease has improved considerably but remains dismal those metastatic recurrent disease.