Molecular and Cellular Biology of F- and V-ATPases
作者： Nathan Nelson
DOI: 10.1007/978-3-662-22265-2_1
关键词: Function (biology) 、 Proton pump 、 Integral membrane protein 、 Chloroplast 、 Mechanism of action 、 ATPase 、 Cell biology 、 Mitochondrion 、 Organelle 、 Chemistry
摘要: There are two mechanistically distinct ATP-dependent proton pumps. One belongs to the family of P-ATPases that operates with a phosphoenzyme intermediate, and second families F- V-ATPases operate without an apparent phospho-enzyme intermediate.1, 2 The P-type pumps integral membrane proteins, having similar structure mechanism action those Na+/K+-ATPases Ca++-ATPases. function this pump is primarily in plasma plant fungal cells specialized mammalian such as parietal stomach.3 more universal at least one them present every living cell.4 They share common have evolutionary ancestry. In eukaryotic F-ATPases confined semiautonomous organelles, chloroplasts mitochondria contain their own genes encoding some F-ATPase subunits.5 also vital for known eubacterium acting photosynthetic or respiratory ATP-formation and/or generating protonmotive force (pmf) by reaction pumping.
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