Natural substances (acetogenins) from the family Annonaceae are powerful inhibitors of mitochondrial NADH dehydrogenase (Complex I).

作者： M Degli Esposti , A Ghelli , M Ratta , D Cortes , E Estornell

关键词: Annonacin 、 Acetogenin 、 Submitochondrial particle 、 NADH dehydrogenase complex 、 Respiratory chain 、 Biology 、 Rotenone 、 Biochemistry 、 Bullatacin 、 Annonaceae 、 Stereochemistry

摘要: … The properties of five of such acetogenins are compared with those of rotenone and piericidin… Note that IC50 for rotenone decreased on increasing the incubation time to more than 4 h. 0…