Direct formation of mesoporous upconverting core-shell nanoparticles for bioimaging of living cells

作者: Lining Sun , Tao Liu , Yannan Qiu , Jinliang Liu , Liyi Shi

DOI: 10.1007/S00604-013-1073-9

关键词: Upconverting nanoparticlesMesoporous materialLaserPhotochemistryCytotoxicityNanochemistryMaterials scienceNanotechnologyCore shell nanoparticlesGreen emissionMesoporous silica

摘要: We have developed a one-step method for the synthesis of mesoporous upconverting nanoparticles (MUCNs) type NaYF4:Yb,Er@mSiO2 in ammoniacal ethanol/water solution. The silica is directly encapsulating hydrophobic upconversion (UCNs) due to presence template CTAB. Intense green emission (between 520 and 560 nm) weaker red 630 670 observed upon 980-nm laser excitation. MUCNs display low cytotoxicity (as revealed by an MTT test) were successfully applied label image human nasopharyngeal epidermal carcinoma (KB) cells.

参考文章(37)
Yonghui Deng, Dawei Qi, Chunhui Deng, Xiangmin Zhang, Dongyuan Zhao, Superparamagnetic High-Magnetization Microspheres with an Fe3O4@SiO2 Core and Perpendicularly Aligned Mesoporous SiO2 Shell for Removal of Microcystins Journal of the American Chemical Society. ,vol. 130, pp. 28- 29 ,(2008) , 10.1021/JA0777584
Hai Sheng Qian, Hui Chen Guo, Paul Chi-Lui Ho, Ratha Mahendran, Yong Zhang, Mesoporous-silica-coated up-conversion fluorescent nanoparticles for photodynamic therapy. Small. ,vol. 5, pp. 2285- 2290 ,(2009) , 10.1002/SMLL.200900692
Niagara Muhammad Idris, Muthu Kumara Gnanasammandhan, Jing Zhang, Paul C Ho, Ratha Mahendran, Yong Zhang, In vivo photodynamic therapy using upconversion nanoparticles as remote-controlled nanotransducers Nature Medicine. ,vol. 18, pp. 1580- 1585 ,(2012) , 10.1038/NM.2933
Daqin Chen, Lei Lei, Anping Yang, Zhaoxing Wang, Yuansheng Wang, Ultra-broadband near-infrared excitable upconversion core/shell nanocrystals Chemical Communications. ,vol. 48, pp. 5898- 5900 ,(2012) , 10.1039/C2CC32102E
Xiaomin Liu, Xianggui Kong, Youlin Zhang, Langping Tu, Yu Wang, Qinghui Zeng, Chunguang Li, Zhan Shi, Hong Zhang, Breakthrough in concentration quenching threshold of upconversion luminescence via spatial separation of the emitter doping area for bio-applications. Chemical Communications. ,vol. 47, pp. 11957- 11959 ,(2011) , 10.1039/C1CC14774A
Bożena Sikora, Krzysztof Fronc, Izabela Kamińska, Kamil Koper, Sebastian Szewczyk, Bohdan Paterczyk, Tomasz Wojciechowski, Kamil Sobczak, Roman Minikayev, Wojciech Paszkowicz, Piotr Stępień, Danek Elbaum, Transport of NaYF4:Er3+, Yb3+ up-converting nanoparticles into HeLa cells. Nanotechnology. ,vol. 24, pp. 235702- ,(2013) , 10.1088/0957-4484/24/23/235702
Ivan Gorelikov, Naomi Matsuura, Single-Step Coating of Mesoporous Silica on Cetyltrimethyl Ammonium Bromide-Capped Nanoparticles Nano Letters. ,vol. 8, pp. 369- 373 ,(2008) , 10.1021/NL0727415
Tianshe Yang, Yun Sun, Qian Liu, Wei Feng, Pengyuan Yang, Fuyou Li, Cubic sub-20 nm NaLuF4-based upconversion nanophosphors for high-contrast bioimaging in different animal species Biomaterials. ,vol. 33, pp. 3733- 3742 ,(2012) , 10.1016/J.BIOMATERIALS.2012.01.063
Jinliang Liu, Yi Liu, Qian Liu, Chunyan Li, Lining Sun, Fuyou Li, Iridium(III) Complex-Coated Nanosystem for Ratiometric Upconversion Luminescence Bioimaging of Cyanide Anions Journal of the American Chemical Society. ,vol. 133, pp. 15276- 15279 ,(2011) , 10.1021/JA205907Y
Zhengquan Li, Yong Zhang, Shan Jiang, Multicolor Core/Shell‐Structured Upconversion Fluorescent Nanoparticles Advanced Materials. ,vol. 20, pp. 4765- 4769 ,(2008) , 10.1002/ADMA.200801056