Evaluation of stool antigen detection for diagnosis of Helicobacter pylori infection in adults.

作者: B Aguemon , M. Struelens , J. Deviere , O. Denis , P. Golstein

DOI: 10.1179/ACB.2004.036

关键词: MedicineGastroenterologyHelicobacter pyloriCase-control studyFecesProspective cohort studyEndoscopySpirillaceaeSurgeryInternal medicineHistologyAntigen

摘要: Objective: The aims of this study were to evaluate the performance Helicobacter pylori stool antigen test in diagnosis H. infection. Method: included 63 out patients attending ULB-Lothier Clinic between January 1 and July 31, 2002. They underwent an upper endoscopy, as well biopsies for histological examination culture pylori. Stool samples these collected either day endoscopy or within 24 hours tested (HpSA Test) Results: mean age 29 men 34 women was 51(± :16) years. infection detected cases (46 %) by histology, 31 (49.2 detection feces. In 27 patients, all methods positive whereas 5 they provided discrepant results. Compared reference (culture histology), HpSA had a sensitivity 96.5% specifi city 91.2%. PPV 90.3% NPV 96.8%. Conclusion: good correlation found results based on supports its use alternative invasive therapeutic follow-up.

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