Use of proteomics for the discovery of early markers of drug toxicity.
作者： Ben C Collins , Ambrose Clarke , Neil R Kitteringham , William M Gallagher , Stephen R Pennington
关键词: Drug toxicity 、 Computational biology 、 Proteomics 、 Pharmacology 、 Toxicity 、 Systems toxicology 、 Biology 、 Predictive toxicology 、 Drug development
摘要: … to better predictive models of toxicity for use in drug development. The field of proteomics continues to develop rapidly and it is already evident that proteomic approaches have much to …
informahealthcare.com参考文章(91)
Wells W. Wu, Guanghui Wang, Seung Joon Baek, Rong-Fong Shen, Comparative study of three proteomic quantitative methods, DIGE, cICAT, and iTRAQ, using 2D gel- or LC-MALDI TOF/TOF Journal of Proteome Research. ,vol. 5, pp. 651- 658 ,(2006) , 10.1021/PR050405O
Rie KIKKAWA, Toshinori YAMAMOTO, Tamio FUKUSHIMA, Hiroshi YAMADA, Ikuo HORII, Investigation of a hepatotoxicity screening system in primary cell cultures --"what biomarkers would need to be addressed to estimate toxicity in conventional and new approaches?". Journal of Toxicological Sciences. ,vol. 30, pp. 61- 72 ,(2005) , 10.2131/JTS.30.61
Michael D. Waters, Jennifer M. Fostel, Toxicogenomics and systems toxicology: aims and prospects Nature Reviews Genetics. ,vol. 5, pp. 936- 948 ,(2004) , 10.1038/NRG1493
Rawiwan Maniratanachote, Keiichi Minami, Miki Katoh, Miki Nakajima, Tsuyoshi Yokoi, Dephosphorylation of ribosomal protein P0 in response to troglitazone-induced cytotoxicity. Toxicology Letters. ,vol. 166, pp. 189- 199 ,(2006) , 10.1016/J.TOXLET.2006.07.303
Leigh Anderson, Christie L. Hunter, Quantitative Mass Spectrometric Multiple Reaction Monitoring Assays for Major Plasma Proteins Molecular & Cellular Proteomics. ,vol. 5, pp. 573- 588 ,(2006) , 10.1074/MCP.M500331-MCP200
B.Kevin Park, Neil R. Kitteringham, Helen Powell, Munir Pirmohamed, Advances in molecular toxicology-towards understanding idiosyncratic drug toxicity. Toxicology. ,vol. 153, pp. 39- 60 ,(2000) , 10.1016/S0300-483X(00)00303-6
Shao-En Ong, Irina Kratchmarova, Matthias Mann, None, Properties of 13C-Substituted Arginine in Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC) Journal of Proteome Research. ,vol. 2, pp. 173- 181 ,(2003) , 10.1021/PR0255708
Robert Tonge, Joanne Shaw, Brian Middleton, Rachel Rowlinson, Steve Rayner, Janice Young, Francois Pognan, Edward Hawkins, Ian Currie, Matthew Davison, Validation and development of fluorescence two‐dimensional differential gel electrophoresis proteomics technology Proteomics. ,vol. 1, pp. 377- 396 ,(2001) , 10.1002/1615-9861(200103)1:3<377::AID-PROT377>3.0.CO;2-6
Cloud P. Paweletz, Matthew C. Wiener, Jeffrey R. Sachs, Roger Meurer, Margaret S. Wu, Kenney K. Wong, Nathan A. Yates, Ronald C. Hendrickson, Surface enhanced laser desorption ionization spectrometry reveals biomarkers for drug treatment but not dose. Proteomics. ,vol. 6, pp. 2101- 2107 ,(2006) , 10.1002/PMIC.200500569
Paul Cutler, David J. Bell, Helen C. Birrell, John C. Connelly, Susan C. Connor, Elaine Holmes, Bob C. Mitchell, Soraya Y. Monté, Bill A. Neville, Russell Pickford, Steven Polley, Klaus Schneider, J. Mark Skehel, An integrated proteomic approach to studying glomerular nephrotoxicity. Electrophoresis. ,vol. 20, pp. 3647- 3658 ,(1999) , 10.1002/(SICI)1522-2683(19991201)20:18<3647::AID-ELPS3647>3.0.CO;2-#