Morphological Characterization of Cell Receptors

摘要: The understanding of what receptors are and how they work began with the “receptor concept” proposed by Ehrlich Langley (1878). coordination thousands interactions between living cells was later realized to be a fundamental mechanism intercellular communication prerequisite for functional integrity multicellular organisms. Receptor proteins essential (a) transmit information from one cell another, (b) transduce signals cellular environment intracellular targets nuclear DNA regulating function, (c) take up special substances in highly controlled manner maintain metabolism, (d) handle toxins artificial drugs. These functions accomplished specific set which can localized membrane, organelles, or cytosol and/or nucleus. A wide variety biochemically very different signal molecules bind these receptor proteins, transporting turn induces reactions.