Allele polymorphism and haplotype diversity of MICA/B in Tujia nationality of Zhangjiajie, Hunan Province, China
作者： Y.J. Wang , N.J. Zhang , E. Chen , C.J. Chen , Y.H. Bu
DOI: 10.1016/J.HUMIMM.2016.03.005
关键词: Genetics 、 Tandem repeat 、 Gene polymorphism 、 Allele 、 Polymorphism (computer science) 、 Haplotype 、 Population 、 Major histocompatibility complex 、 Linkage disequilibrium 、 Biology
摘要: Previous studies indicate the distribution of major histocompatibility complex class I chain-related genes A (MICA) and B (MICB) alleles haplotypes varies widely between different ethnic populations geographic areas. It is meaningful to investigate allelic frequencies establish a genetic database. In this study, we firstly reported polymorphic variation MICA/B in 187 healthy, unrelated Tujia individuals Zhangjiajie region, China. Using polymerase chain reaction-sequence specific priming (PCR-SSP) sequencing-based typing (PCR-SBT), identified eight MICA-sequence alleles, four MICA-short tandem repeat variants, 13 MICB which MICA(∗)008:04 (29.41%), MICA(∗)A5 (29.68%), MICA(∗)A5.1 (29.68%) MICB(∗)005:02 (39.57%) were most frequent. Linkage disequilibrium analysis further revealed MICB(∗)005:02-MICA(∗)019 (13.10%) MICB(∗)002-MICA(∗)008:04 (9.89%) as common two-locus haplotypes. Data comparison by neighbor-joining dendrograms principal component verify other Chinese Asia groups showed that Tujias genetically closer Guangdong Han population, based on MICA loci variability. Our results provide new information about gene polymorphism will form basis for future potential role allogeneic organ transplantation disease susceptibility related groups.
sci-hub.se 参考文章(46)
Seiamak Bahram, MIC genes: from genetics to biology. Advances in Immunology. ,vol. 76, pp. 1- 60 ,(2000) , 10.1016/S0065-2776(01)76018-X
H. H. Hattemer, Genetic distance between populations Theoretical and Applied Genetics. ,vol. 62, pp. 219- 223 ,(1982) , 10.1007/BF00276242
L. Lin, W. Yang, E. Chen, Z. Gong, Q. Z. Luo, X. B. Wei, P. Yu, MIC gene polymorphism and haplotype diversity in Li nationality of Southern China: MIC polymorphism and haplotype diversity in Li nationality of China Tissue Antigens. ,vol. 85, pp. 45- 49 ,(2015) , 10.1111/TAN.12449
Shigehiro Tamaki, Nobuyuki Sanefuzi, Kazuhiko Ohgi, Yuichiro Imai, Masayoshi Kawakami, Kazuhiko Yamamoto, Akiko Ishitani, Katsuhiko Hatake, Tadaaki Kirita, An association between the MICA-A5.1 allele and an increased susceptibility to oral squamous cell carcinoma in Japanese patients. Journal of Oral Pathology & Medicine. ,vol. 36, pp. 351- 356 ,(2007) , 10.1111/J.1600-0714.2007.00539.X
Segundo Gonzalez, J. Martinez-Borra, J. C. Torre-Alonso, S. Gonzalez-Roces, J. Sanchez Del R�o, A. Rodriguez P�rez, Chaim Brautbar, C. L�pez-Larrea, The MICA-A9 triplet repeat polymorphism in the transmembrane region confers additional susceptibility to the development of psoriatic arthritis and is independent of the association of Cw*0602 in psoriasis. Arthritis & Rheumatism. ,vol. 42, pp. 1010- 1016 ,(1999) , 10.1002/1529-0131(199905)42:5<1010::AID-ANR21>3.0.CO;2-H
Wei Tian, Jin H. Cai, Fan Wang, Li X. Li, MICA polymorphism in a northern Chinese Han population: The identification of a new MICA allele, MICA*059 Human Immunology. ,vol. 71, pp. 423- 427 ,(2010) , 10.1016/J.HUMIMM.2010.01.025
Li Zhang, Dangxiao Cheng, Ning Tao, Min Zhao, Fan Zhang, Yulin Yuan, Xiaoping Qiu, None, Distribution of HLA-A, -B and-DRB1 Genes and Haplotypes in the Tujia Population Living in the Wufeng Region of Hubei Province, China PLOS ONE. ,vol. 7, ,(2012) , 10.1371/JOURNAL.PONE.0038774
Daniela Piancatelli, Tiziana Del Beato, Khadija Oumhani, Rajae El Aouad, Domenico Adorno, MICA polymorphism in a population from north Morocco, Metalsa Berbers, using sequence-based typing. Human Immunology. ,vol. 66, pp. 931- 936 ,(2005) , 10.1016/J.HUMIMM.2005.06.008
A.V. Romphruk, T.K. Naruse, A. Romphruk, H. Kawata, C. Puapairoj, J.K. Kulski, C. Leelayuwat, H. Inoko, Diversity of MICA (PERB11.1) and HLA haplotypes in Northeastern Thais Tissue Antigens. ,vol. 58, pp. 83- 89 ,(2001) , 10.1034/J.1399-0039.2001.580203.X
F. Zhu, H. Zhao, Y. He, W. Zhang, J. He, X. Xu, L. Yan, Distribution of MICA diversity in the Chinese Han population by polymerase chain reaction sequence-based typing for exons 2-6. Tissue Antigens. ,vol. 73, pp. 358- 363 ,(2009) , 10.1111/J.1399-0039.2009.01225.X