Functional Diversity of Soil Microbial Communities in Response to the Application of Cefuroxime and/or Antibiotic-Resistant Pseudomonas putida Strain MC1

摘要: Cefuroxime (XM), the most commonly prescribed antibiotic from cephalosporin group, may cause changes in structure of soil microbial community, and these also be reflected alteration its functionality. Therefore, due to lack studies on this topic, scope study was assess functional diversity catabolic activity community treated with XM (1 mg/kg 10 soil) using community-level physiological profile (CLPP) approach during a 90-day experiment. In addition, effect antibiotic-resistant Pseudomonas putida strain MC1 (Ps) evaluated. The resistance/resilience concept multifactorial analysis were used interpret data. results showed that introduction and/or Ps into caused community. A decrease values CLPP indices (i.e., expressed as average well-color development (AWCD), substrate richness (R), Shannon-Wiener (H) evenness (E) AWCD for six carbon groups) XM-treated generally detected up 30 days. turn, at same time, measured Ps-inoculated higher compared control soil. stimulatory (XM10) XM10+Ps utilization pattern each group found following sampling times (days 60 90). amines, amino acids, carbohydrates, carboxylic miscellaneous compounds polymers treatments 2.3-, 3.1-, 13-, 3.4- 3.3-fold nontreated control, respectively. resistance groups categorized follows: E > H R acids = carbohydrates amines suggest low initial Ps, despite short-term negative effect, balance ecosystem disturbed.