The association between serum zinc level and overweight/obesity: a meta-analysis
作者： Kunfang Gu , Wenzhi Xiang , Yue Zhang , Ke Sun , Xiubo Jiang
DOI: 10.1007/S00394-018-1876-X
关键词: Meta-analysis 、 Medicine 、 Overweight obesity 、 Confidence interval 、 Internal medicine 、 Systematic search 、 Strictly standardized mean difference 、 Obesity 、 Gastroenterology 、 Serum zinc level 、 Overweight
摘要: The association between serum zinc level and overweight/obesity remains controversial. Hence, we performed a meta-analysis to summarize the relationships. A systematic literature search was in PubMed, Web of Science Embase for relevant English articles up April 20, 2018. pooled standardized mean difference (SMD) with 95% confidence interval (CI) calculated random-effect model. For children adults, results showed that significantly lower cases compared controls ([SMD (95% CI): − 1.13 (− 2.03, − 0.23), Z = 2.45, P Z = 0.014; I2 = 97.1%, I2 < 0.001] [SMD − 0.41 (− 0.68, − 0.15), Z = 3.03, Z = 0.002; I2 = 62.9%, I2 = 0.009], respectively). overweight adults not statistically significant − 0.09 (− 0.27, 0.09), Z = 0.97, Z = 0.334; I2 = 0.0%, I2 = 0.411]. In subgroup analyses, obese non-obese observed − 2.14 (− 3.20, − 1.09)], SMD differ case–control studies − 0.49 (− 0.90, − 0.08)]. Our suggested adults. More large observational are required confirm these future research.
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