Expression of the transcription factor ΔFosB in the brain controls sensitivity to cocaine

作者: Max B. Kelz , Jingshan Chen , William A. Carlezon , Kim Whisler , Lauren Gilden

DOI: 10.1038/45790

关键词: Nucleus accumbensAddictionNicotinePharmacologyPhencyclidineEpigenetics of cocaine addictionBiologyAmphetamineFOSBAMPA receptor

摘要: Acute exposure to cocaine transiently induces several Fos family transcription factors in the nucleus accumbens 1 , a region of the brain that is important for addiction 2 , 3 . In contrast, …

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