Infection rate in total hip arthroplasty as a function of air cleanliness and antibiotic prophylaxis

摘要: To separate the respective effects of sterile air and antibiotic prophylaxis in orthopedic surgery, authors reviewed 2,384 cementless total hip replacements performed from 1975 to 1984 for incidence deep sepsis. During this period, a conventionally ventilated room (100 particle-forming units (pfu)/m3) laminar vertical flow (1 pfu/m3) were alternately used, without significant difference sepsis rate. Beginning 1979, prophylactic regimen was added, which 1979 reduced 2.78% 0.52%. There also change common infecting organisms, sensitive resistant strains, is not an insignificant consequence.