A case of post-traumatic minimally conscious state reversed by midazolam: Clinical aspects and neurophysiological correlates.
作者： Maria Chiara Carboncini , Andrea Piarulli , Alessandra Virgillito , Pieranna Arrighi , Paolo Andre
DOI: 10.3233/RNN-140426
关键词: Persistent vegetative state 、 Functional brain 、 Psychology 、 Minimally conscious state 、 Midazolam 、 Functional networks 、 Electroencephalography 、 Neurophysiology 、 Neuroscience 、 Maximum difference
摘要: Purpose We describe the case of a subject in post-traumatic Minimally Conscious State (MCS) who retrieved full interaction with environment after midazolam infusion. studied EEG correlates "awakening reaction" different domains frequency, time and cortical topography, along intrinsic connectivity within both task-positive linguistic network. Methods recorded before administration has been submitted to spectral power analysis, sLORETA analysis functional networks. Results A critical change spectrum profile was observed midazolam: a) between 1 12 Hz decreased, reaching its maximum difference respect pre-infusion at about 7 b) 30 increased, 15 Hz. At same time, induced significant changes, especially for these two frequency bands, Conclusions advance some hypotheses certain aspects recovery from MCS terms anatomo-functional correlations brain systems we make inferences role that kind 'catatonic' symptoms might play determining and/or maintaining this peculiar clinical state.
sci-hub.se 参考文章(70)
Ralf Clauss, Wally Nel, Effect of zolpidem on brain injury and diaschisis as detected by 99mTc HMPAO brain SPECT in humans. Drug Research. ,vol. 54, pp. 641- 646 ,(2011) , 10.1055/S-0031-1297015
Pedro A. Valdés-Hernández, Nicolás von Ellenrieder, Alejandro Ojeda-Gonzalez, Silvia Kochen, Yasser Alemán-Gómez, Carlos Muravchik, Pedro A. Valdés-Sosa, Approximate average head models for EEG source imaging Journal of Neuroscience Methods. ,vol. 185, pp. 125- 132 ,(2009) , 10.1016/J.JNEUMETH.2009.09.005
S. LAUREYS, C. LEMAIRE, P. MAQUET, C. PHILLIPS, G. FRANCK, Cerebral metabolism during vegetative state and after recovery to consciousness Journal of Neurology, Neurosurgery, and Psychiatry. ,vol. 67, pp. 121- 122 ,(1999) , 10.1136/JNNP.67.1.121
Hyo Jung Kang, Yuka Imamura Kawasawa, Feng Cheng, Ying Zhu, Xuming Xu, Mingfeng Li, André M. M. Sousa, Mihovil Pletikos, Kyle A. Meyer, Goran Sedmak, Tobias Guennel, Yurae Shin, Matthew B. Johnson, Željka Krsnik, Simone Mayer, Sofia Fertuzinhos, Sheila Umlauf, Steven N. Lisgo, Alexander Vortmeyer, Daniel R. Weinberger, Shrikant Mane, Thomas M. Hyde, Anita Huttner, Mark Reimers, Joel E. Kleinman, Nenad Šestan, Spatio-temporal transcriptome of the human brain Nature. ,vol. 478, pp. 483- 489 ,(2011) , 10.1038/NATURE10523
S J M Smith, EEG in the diagnosis, classification, and management of patients with epilepsy Journal of Neurology, Neurosurgery & Psychiatry. ,vol. 76, pp. ii2- ii7 ,(2005) , 10.1136/JNNP.2005.069245
Christopher Torrence, Gilbert P. Compo, A Practical Guide to Wavelet Analysis. Bulletin of the American Meteorological Society. ,vol. 79, pp. 61- 78 ,(1998) , 10.1175/1520-0477(1998)079<0061:APGTWA>2.0.CO;2
Steven Laureys, Mélanie Boly, Pierre Maquet, Tracking the recovery of consciousness from coma. Journal of Clinical Investigation. ,vol. 116, pp. 1823- 1825 ,(2006) , 10.1172/JCI29172
Zbyněk Šidák, Rectangular Confidence Regions for the Means of Multivariate Normal Distributions Journal of the American Statistical Association. ,vol. 62, pp. 626- 633 ,(1967) , 10.1080/01621459.1967.10482935
Yun Qin, Peng Xu, Dezhong Yao, A comparative study of different references for EEG default mode network: The use of the infinity reference Clinical Neurophysiology. ,vol. 121, pp. 1981- 1991 ,(2010) , 10.1016/J.CLINPH.2010.03.056
Leonides Canuet, Ryouhei Ishii, Roberto D. Pascual-Marqui, Masao Iwase, Ryu Kurimoto, Yasunori Aoki, Shunichiro Ikeda, Hidetoshi Takahashi, Takayuki Nakahachi, Masatoshi Takeda, Resting-State EEG Source Localization and Functional Connectivity in Schizophrenia-Like Psychosis of Epilepsy PLoS ONE. ,vol. 6, pp. e27863- ,(2011) , 10.1371/JOURNAL.PONE.0027863