Evaluation of calcium metabolism and pituitary gonadotropin secretion during treatment with nifedipine

摘要: The clinical use of calcium antagonist drugs in cardiology theoretically may interfere with the endocrine secretions. Actually ion appears to be primarily involved stimulus-secretion and excitation-contraction coupling. This paper is evaluate influence, vivo, nifedipine on metabolism, FSH LH level plasmatic calcium, parathyroid hormone (PTH), FSH, secretion were observed seven patients under cronic treatment. plasmic hormones investigation was tested radioimmunoassay method. Neither nor levels had significant variations during 28 days control period. From our data we can infer that long term treatment has no influence metabolism gonadotropic secretions, even though such an been demonstrated "in vivo" studies.