Prolonged post-block hypoexcitability induced by anodal blockade of cat tooth pulp.

作者: R.Wayne Fields , Richard B. Tacke , Richard J. Beale , Bhim Sen Savara

DOI: 10.1016/0014-4886(76)90004-2

关键词: ElectroanalgesiaMembrane hyperpolarizationStimulationPulp (tooth)BlockadeMedicineAnatomyAnesthesiaCanine toothControl level

摘要: Abstract Stimulation of the canine tooth pulp in barbiturized cat was used to elicit trigeminal field potentials as an index pulpal excitability. The purpose present experiment characterize magnitude and temporal pattern a dose-dependent attenuation excitability induced during following application direct anodal blocking currents (electroanalgesia) test tooth. electroanalgesia current resulted hypoexcitability which, with rare exception, tended progressively increase time. Following cessation all but quite low levels block, (by either monopolar or bipolar testing) never returned its control level, remained elevated occasionally became more intense for several hours dependent on intensity duration current. These characteristics imply changes unlikely result solely from “pure” membrane hyperpolarization classical block hypothesis.

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