Chronic diet-induced hyperhomocysteinemia impairs eNOS regulation in mouse mesenteric arteries

作者: Robin C. Looft-Wilson , Blair S. Ashley , Janelle E. Billig , Madeline R. Wolfert , Lindsay A. Ambrecht

DOI: 10.1152/AJPREGU.00833.2007

关键词: Nitric oxide synthaseInternal medicineNitric oxideVasodilationBiologyEndocrinologyNitric Oxide Synthase Type IIIEnosEndotheliumHyperhomocysteinemiaMesenteric arteries

摘要: Hyperhomocysteinemia (HHcy) impairs endothelium-dependent vasodilation by increasing reactive oxygen species, thereby reducing nitric oxide (NO·) bioavailability. It is unclear whether reduced expr...

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