A combined micro-solid phase-single drop microextraction approach for trace enrichment of volatile organic compounds

摘要: An attempt was made to combine μ-solid phase extraction and headspace single drop microextraction techniques use their advantages for trace determination of some volatile organic compounds in aqueous samples. After performing the two-step preconcentration approach, desired analytes were determined by gas chromatography-mass spectrometry. A resorcinol-formaldehyde-based xerogel used as medium (μ-SPE) method. Then, extracted BTEX eluted with a rather large amount methanol. To remove laborious process including solvent evaporation further reconstitution, which is usually accompanied loss accuracy, (HS-SDME) employed second orthogonal enrichment technique. The combination these two led factors ranging from 118 504 indicating enhanced capability method towards aromatic compounds. Under optimum conditions, limit detection (LOD) varied 0.03 0.1 μg L−1 linearity range 0.1–100 L−1, while RSD% values (n = 5) all satisfactory at concentration levels 100 L−1. applicability developed μ-SPE/HSSDME/GC-MS examined analyzing river paddy water samples acceptable relative recovery percentages obtained.