Antiseptics for treating infected wounds: Efficacy on biofilms and effect of pH

作者: Steven L. Percival , Simon Finnegan , Gianfranco Donelli , Claudia Vuotto , Steve Rimmer

DOI: 10.3109/1040841X.2014.940495

关键词: Delayed healingBiofilmAntimicrobial efficacyAntimicrobialMicrobiologyMedicine

摘要: Biofilm recalcitrance is a persistent problem when managing difficult to heal and infected chronic wounds. The wound biofilm fundamental factor in the re-occurrence delayed healing commonly observed non-healing However, there presently no single antimicrobial agent that completely efficacious against both planktonic sessile polymicrobial communities evident at risk or We will review currently available antimicrobials, with particular emphasis on silver iodine, employed help suppress biofilms In addition, we also effect of pH efficacy. Available evidence suggests it best take multifactorial approach towards controlling chronic, "at risk" This highlights growing importance avoiding indiscriminate inappropriate use antimicrobials treatment

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