Nanopore sequencing using charge blockade labels
作者： Jeffrey Wegener , Stephen Turner
DOI:
关键词: Nanopore 、 Combinatorial chemistry 、 Biochemistry 、 Polymerase 、 Nucleic acid 、 Nucleotide 、 Enzyme 、 Nanopore sequencing 、 Sequence (biology) 、 Biology 、 Enzyme complex
摘要: The invention relates to devices and methods for nanopore sequencing. includes compositions of nucleic acid sequencing using a single polymerase enzyme complex comprising template attached proximal nanopore, nucleotide analogs in solution charge blockade label that are the polyphosphate portion analog such labels cleaved when is incorporated into growing detected by determine presence identity thereby sequence acid.
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