The neural basis of nonword repetition in children with developmental speech or language disorder: An fMRI study

摘要: Developmental language disorder (DLD) and developmental speech (DSD) are highly prevalent childhood conditions. An impaired ability to repeat nonsense words ("nonword repetition"), is claimed be a robust behavioural marker for these Yet how brain function altered during this task remains poorly understood. Previous research suggests that DLD or DSD may associated with reduced activation in the inferior frontal posterior temporal regions when compared controls. However, limited by within between group variability age, speech/language phenotype, comorbidities. Here, we used functional MRI examine nonword repetition. As anticipated, findings confirmed groups had poorer repetition performance typical In contrast, fMRI revealed no statistically significant differences activation, despite appearing engage slightly different at identical thresholds. Therefore, whilst sensitive clinical DSD, from study suggest not children disorders, unlike individuals single gene mutations like FOXP2 mutations.