A state-wide initiative to promote genetic testing in an underserved population.

摘要: Genetic testing for cancer susceptibility has been widely studied and utilized clinically. Access to genetic services in research practice is largely limited well-insured, Caucasian individuals. In 2009, the Cancer Resource Foundation (CRF) implemented Information Treatment Surveillance Support (GIFTSS) program cover out-of-pocket expenses associated with testing, targeting high-risk individuals financial means health insurance coverage. Here, we (i) describe characteristics of participants Massachusetts (MA) GIFTSS (ii) evaluate mutations found this diverse sample. A secondary retrospective data analysis was performed using de-identified demographic obtained from laboratory requisition forms result information source. Eligible were those who MA GIFFTS 2009 through December 2014. Data summarized descriptive measures central tendency. Participants residents had a reported income within 250-400% federal poverty level. results categorized following clinical guidelines. Overall, 123 (13%) tested positive mutation gene. For diagnosis, 65 (12%) have 20 (7%) variant uncertain significance (VUS). unaffected patients, 58 (15%) 10 (3%) VUS. The study are useful describing outcomes underserved community. Repeatedly, literature reports that or resource settings less likely access testing. Continued efforts should be devoted promoting high-risk,