Polygenic overlap and shared genetic loci between loneliness, severe mental disorders, and cardiovascular disease risk factors suggest shared molecular mechanisms
作者： Linn Rødevand , Shahram Bahrami , Oleksandr Frei , Aihua Lin , Osman Gani
DOI: 10.1038/S41398-020-01142-4
关键词: Genetic correlation 、 Genetics 、 Bipolar disorder 、 Loneliness 、 Schizophrenia 、 Depression (differential diagnoses) 、 Genetic architecture 、 Biology 、 Epidemiology 、 Disease
摘要: … Altogether, the study revealed polygenic overlap between loneliness, SMDs and CVD risk factors, providing new insights into their shared genetic architecture and common genetic …
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