Fermented barley extract suppresses the development of atopic dermatitis-like skin lesions in NC/Nga mice, probably by inhibiting inflammatory cytokines.

摘要: We have found that fermented barley extract (FBE), prepared from shochu residue, alleviates allergic rhinitis in OVA-sensitized mice. In this study, we examined to determine whether FBE suppresses the development of atopic dermatitis (AD)-like skin lesions NC/Nga The AD-like a 5% containing diet group was significantly inhibited, and scratching behavior, one aggravating factors, also suppressed. Neither serum immunoglobulin E (IgE) levels nor interleukin (IL)-4 production by spleen cells be reduced. On other hand, interferon-gamma (IFN-γ) IL-17 Hence it assumed mice, probably modulating cytokine involved chronic inflammation, such as IFN-γ or IL-17.