High-throughput quantification of carboxymethyl lysine in serum and plasma using high-resolution accurate mass Orbitrap mass spectrometry.

作者: Naomi J Rankin , Karl Burgess , Stefan Weidt , Goya Wannamethee , Naveed Sattar

DOI: 10.1177/0004563219830432

关键词: Throughput (business)OrbitrapAdvanced glycation end-productMass spectrometryPotential biomarkersIsotope dilutionHigh resolutionLysineChemistryChromatography

摘要: BackgroundCarboxymethyl lysine is an advanced glycation end product of interest as a potential biomarker cardiovascular and other diseases. Available methods involve ELISA, with interf...

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