Quantitative distribution of vitamin A in Kupffer cell and hepatocyte populations of rat liver.

作者: Maria C. Linder , G. Harvey Anderson , Immanuel Ascarelli

DOI: 10.1016/S0021-9258(18)61942-8

关键词: PopulationInternal medicineRetinolDistribution (pharmacology)Kupffer cellEndocrinologyLiver cellRat liverVitaminHepatocyteChemistry

摘要: Abstract Kupffer cells were isolated from livers of rats on normal and excess vitamin A diets their content was compared with that the whole which they had been isolated. In all cases, per cell found to be less than one-tenth average liver cell, population calculated contain 4% total vitamin, rest being present in hepatocytes. The same distribution 1 hour after its intravenous infusion as [14C]retinol.

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