Developmental Toxicity of Metals: Implications for Public Health

作者: J. Julian Chisolm , David J. Thomas

DOI: 10.1007/978-1-4615-9346-1_24

关键词: ToxicologyPublic healthEpidemiologyDevelopmental toxicityNational Health and Nutrition Examination SurveyEnvironmental healthFamily incomeMedicineWhole bloodDeveloped countryPopulation

摘要: The second National Health and Nutrition Examination Survey (NHANES II) conducted between 1976 1980 has provided the most comprehensive epidemiological assessment of lead absorption in general population ever made United States. data indicate that an estimated 4.0 percent, or approximately 675,000 children, aged six months to five years, have blood concentrations greater than upper limit currently accepted “normal” range, namely ≥ 30 μg Pb/dl whole blood. influence family income residence is striking. Increased (PbB μg, PbB = blood) highest among low urban black children (18.6 percent) lowest rural white (1.2 percent). NHANES II suggest average for entire decreased from 15.8 10 ng 1980. This decrease may reflect decreases both content food use additives gasoline. If this trend confirmed, it likely only old deteriorated lead-painted housing will remain as primary environmental source young prevalence increased States data, appears higher based upon reports other industrialized countries.

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