Characterization and Some Physicochemical Aspects of Pathological Microcalcifications

摘要: Several major diseases, such as cancer and cardiovascular abnormalities, may be linked to pathological deposition of minerals or organic compounds in various tissues. Thus, the detection understanding physicochemical processes associated with their formation are essential. As underlined by Schmidt et al., Europe U.S., breast will occur 1 10 women. If clustered calcifications one mammographic signs early cancer, chemical nature must determined. More precisely, calcium phosphates (CaPs) frequently malignancy, but oxalates present benign lesions. From a medical viewpoint, refer at least three very different families biominerals: concretions, metastatic dystrophic calcifications. Concretions found hollow organs ducts body. For example, kidney stones solid concretions dissolved urine kidney. In contrast, calcifications, which can considered ectopic defined unexpected biomineralization occurring soft absence systemic mineral imbalance, calcification is often tissue alteration necrosis. resulting from imbalance more affect tissues (e.g., vessels, lungs, kidneys). A fourth family physiological (bone), becomes diseases arthrosis osteoporosis.