Geographic and temporal variations in the utilization of stereotactic radiosurgery for treatment of non-small cell lung cancer brain metastases from 2010 to 2015: An analysis of the national cancer database
作者： James M. Wright , Mustafa Ascha , Christina Huang Wright , Gabriel Smith , Carlito Lagman
DOI: 10.1016/J.INAT.2019.100580
关键词: Cancer 、 Radiosurgery 、 Lung cancer 、 Geographic regions 、 Survival benefit 、 Non small cell 、 Internal medicine 、 Oncology 、 Population 、 North central 、 Medicine
摘要: Abstract Purpose This work describes trends in the utilization and survival benefit of stereotactic radiosurgery (SRS) with respect to geographic region United States year diagnosis among patients NSCLC synchronous brain metastases. Methods Patients metastases (2010–2015) were identified NCDB. Descriptive statistics calculated across case SRS region. Univariable multivariable regression performed identify predictors treatment overall population estimate region-specific models hazard mortality over each year. Results Among 49,048 cases metastases, 8310 treated SRS. Those Middle Atlantic had greatest odds treatment, at 1.03 times those East North Central (95% CI: 1.02–1.04, p Conclusion Increased was observed decreased five diagnosis-years These suggest clinical burden secondary cancers, particularly will increase years come.
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