Analysis of the Interaction of IGF-I Analogs with the IGF-I Receptor and IGF Binding Proteins
作者： Margaret A. Cascieri , Marvin L. Bayne
DOI: 10.1007/978-1-4615-2988-0_4
关键词: Cell biology 、 IGF-I Receptor 、 IGF-Binding Proteins 、 Molecular cloning 、 Receptor 、 Homologous chromosome 、 IGF Receptor 、 Chemistry
摘要: The characterization of the various species IGF binding proteins (IGFBPs) by molecular cloning has revealed a large family highly homologous soluble with high affinity for both IGF-I and IGF-II. type 1 receptor IGFBPs appear to form complex regulatory system transducing modulating activity determination roles these in action been facilitated use analogs that selectively bind either or IGFBPs.
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