Synthesis, crystal structures and characterizations of three new copper(II) complexes including anti-inflammatory diclofenac.

摘要: Three new diclofenac-based copper(II) complexes, namely tetra­kis­{μ-2-[2-(2,6-di­chloro­anilino)phen­yl]acetato-κ2O:O′}bis­(methanol-κO)copper(II), [Cu2(μ-dicl)4(CH3OH)2] (1), bis­{2-[2-(2,6-di­chloro­anilino)phen­yl]acetato-κ2O,O′}bis­(1-vinyl-1H-imidazole-κN3)copper(II), [Cu(dicl)2(vim)2] (2), and bis­{2-[2-(2,6-di­chloro­anilino)phen­yl]acetato-κ2O,O′}bis­(1H-imidazole-κN3)copper(II), [Cu(dicl)2(im)2] (3) [dicl is diclofenac (C14H10Cl2NO2), vim 1-vinyl­imidazole (C5H6N2) im imidazole (C3H4N2)], have been synthesized char­ac­ter­ized by elemental analysis, FT–IR spectroscopy, thermal analysis single-crystal X-ray diffraction. diffraction shows that complex 1 consists of dimeric units in which the dicl ligand exhibits a bidentate syn,syn-μ2 coordination mode linking two centres. Complexes 2 3 mononuclear with general formula [Cu(dicl)2L2] (L or im) CuII ions are octa­hedrally coordinated L chelating ligands. The ligands both occupy trans positions octa­hedron. different modes title complexes were revealed Fourier transform IR (FT–IR) spectroscopy. spin matching between centres was also confirmed magnetic data to be lower than spin-only value electron paramagnetic resonance (EPR) spectra. properties investigated thermogravimetric (TG) differential (DTA) techniques.