Appetite and Reward Signals in the Brain: Sugar Intake Effects on Brain Activity as Measured by Functional Magnetic Resonance Imaging

作者: Samantha M. Hudgins , Anna Schlappal , Thomas W. Castonguay

DOI: 10.1016/B978-0-12-407869-7.00028-3

关键词: AmygdalaAppetiteFood intakeBrain activity and meditationInternal medicineSugar intakeFrontal cortexFunctional magnetic resonance imagingEndocrinologyPsychology

摘要: Functional magnetic resonance imaging (fMRI) is a relatively new tool used to monitor the brain’s responses changes in diet. In this chapter, we summarize rapidly growing literature on how brain responds sugar, as measured by blood oxygenated level dependent (i.e. BOLD) fMRI analyses. The chapter starts providing an overview of what known about control food intake, from hypothalamic mechanisms hindbrain-sensory integration reward mechanisms. We then available work measuring response different sugars, including analyses focusing not only glucose, sucrose, and fructose but also several extra regions, amygdala frontal cortex. believe that these will ultimately contribute better understanding sweetened beverages are readily consumed excess need bypassing for controlling intake.

参考文章(37)
I. S. Farooqi, E. Bullmore, J. Keogh, J. Gillard, S. O'Rahilly, P. C. Fletcher, Leptin Regulates Striatal Regions and Human Eating Behavior Science. ,vol. 317, pp. 1355- 1355 ,(2007) , 10.1126/SCIENCE.1144599
ANTHONY SCLAFANI, Learned Controls of Ingestive Behaviour Appetite. ,vol. 29, pp. 153- 158 ,(1997) , 10.1006/APPE.1997.0120
E A Rabiner, J Beaver, A Makwana, G Searle, C Long, P J Nathan, R D Newbould, J Howard, S R Miller, M A Bush, S Hill, R Reiley, J Passchier, R N Gunn, P M Matthews, E T Bullmore, Pharmacological differentiation of opioid receptor antagonists by molecular and functional imaging of target occupancy and food reward-related brain activation in humans Molecular Psychiatry. ,vol. 16, pp. 826- 835 ,(2011) , 10.1038/MP.2011.29
K. D'Ardenne, S. M. McClure, L. E. Nystrom, J. D. Cohen, BOLD responses reflecting dopaminergic signals in the human ventral tegmental area. Science. ,vol. 319, pp. 1264- 1267 ,(2008) , 10.1126/SCIENCE.1150605
Mariska E. Kret, Carsten K. W. De Dreu, Oxytocin-Motivated Ally Selection is Moderated by Fetal Testosterone Exposure and Empathic Concern. Frontiers in Neuroscience. ,vol. 7, pp. 1- 1 ,(2013) , 10.3389/FNINS.2013.00001
Csaba Szalay, Mihály Aradi, Attila Schwarcz, Gergely Orsi, Gábor Perlaki, Lívia Németh, Sophia Hanna, Gábor Takács, István Szabó, László Bajnok, András Vereczkei, Tamás Dóczi, József Janszky, Sámuel Komoly, Péter Örs Horváth, László Lénárd, Zoltán Karadi, None, Gustatory perception alterations in obesity: an fMRI study. Brain Research. ,vol. 1473, pp. 131- 140 ,(2012) , 10.1016/J.BRAINRES.2012.07.051
J. Q. Purnell, B. A. Klopfenstein, A. A. Stevens, P. J. Havel, S. H. Adams, T. N. Dunn, C. Krisky, W. D. Rooney, Brain functional magnetic resonance imaging response to glucose and fructose infusions in humans Diabetes, Obesity and Metabolism. ,vol. 13, pp. 229- 234 ,(2011) , 10.1111/J.1463-1326.2010.01340.X
Jayaram Chandrashekar, Mark A. Hoon, Nicholas J. P. Ryba, Charles S. Zuker, The receptors and cells for mammalian taste Nature. ,vol. 444, pp. 288- 294 ,(2006) , 10.1038/NATURE05401