Cost of illness and economic burden of chronic lymphocytic leukemia.

摘要: Chronic lymphocytic leukemia (CLL) is a slowly progressing but fatal disease that imposes high economic burden on sickness funds and society. The objective of this study was to analyze compare the direct indirect costs CLL in Germany from perspective society disease. Using database 7.6 million enrolled individuals, we identified 4198 patients 2007 2008. attributable were estimated using case–control design with randomly selected control group 150 individuals per combination age sex. We used bootstrap approach estimate uncertainties estimated. employed generalized estimating equation regression models count data test for differences healthcare utilization. cost each prevalent case amounts €4946 payer’s €7910 societal perspective. Inpatient hospital stays pharmaceuticals are main drivers be approximately €201 year €322 Compared common diseases, such as diabetes or COPD, considerably lower. However, treatment about twice these even though only performed later stages CLL. With new technologies, aging population, increasing incidence disease, it likely will continue grow.