作者: Maryline Foerster , Pedro Marques-Vidal , Gerhard Gmel , Jean-Bernard Daeppen , Jacques Cornuz
DOI: 10.1016/J.AMJCARD.2008.09.089
关键词: Internal medicine 、 Medicine 、 Cholesterol 、 Blood pressure 、 High-density lipoprotein 、 Risk assessment 、 Coronary artery disease 、 Alcohol 、 Population 、 Cardiology 、 Framingham Risk Score
摘要: Moderate alcohol consumption has been associated with lower coronary artery disease (CAD) risk. However, data on the CAD risk high are conflicting. The aim of this study was to examine impact heavier drinking 10-year in a population mean consumption. In population-based 5,769 adults (aged 35 75 years) without cardiovascular Switzerland, 1-week categorized as 0, 1 6, 7 13, 14 20, 21 27, 28 34, and ≥35 drinks/week or nondrinkers (0 drinks/week), moderate (1 13 (14 34 very (≥35 drinks/week). Blood pressure lipids were measured, calculated according Framingham score. Seventy-three percent (n = 4,214) participants consumed alcohol; 16% 909) drinkers 2% 119) drinkers. multivariate analysis, increasing higher high-density lipoprotein cholesterol (from ± SE 1.57 0.01 mmol/L 1.88 0.03 drinkers); triglycerides (1.17 1.01 1.32 1.05 mmol/L), systolic diastolic blood (127.4 0.4 132.2 1.4 mm Hg 78.7 0.3 81.7 0.9 Hg, respectively) (all p values for trend