Alcohol drinking and cardiovascular risk in a population with high mean alcohol consumption

作者: Maryline Foerster , Pedro Marques-Vidal , Gerhard Gmel , Jean-Bernard Daeppen , Jacques Cornuz

DOI: 10.1016/J.AMJCARD.2008.09.089

关键词: Internal medicineMedicineCholesterolBlood pressureHigh-density lipoproteinRisk assessmentCoronary artery diseaseAlcoholPopulationCardiologyFramingham Risk Score

摘要: Moderate alcohol consumption has been associated with lower coronary artery disease (CAD) risk. However, data on the CAD risk high are conflicting. The aim of this study was to examine impact heavier drinking 10-year in a population mean consumption. In population-based 5,769 adults (aged 35 75 years) without cardiovascular Switzerland, 1-week categorized as 0, 1 6, 7 13, 14 20, 21 27, 28 34, and ≥35 drinks/week or nondrinkers (0 drinks/week), moderate (1 13 (14 34 very (≥35 drinks/week). Blood pressure lipids were measured, calculated according Framingham score. Seventy-three percent (n = 4,214) participants consumed alcohol; 16% 909) drinkers 2% 119) drinkers. multivariate analysis, increasing higher high-density lipoprotein cholesterol (from ± SE 1.57 0.01 mmol/L 1.88 0.03 drinkers); triglycerides (1.17 1.01 1.32 1.05 mmol/L), systolic diastolic blood (127.4 0.4 132.2 1.4 mm Hg 78.7 0.3 81.7 0.9 Hg, respectively) (all p values for trend

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