Dopamine and Dopaminergic Ligands
作者： Alan F. Casy , George H. Dewar
DOI: 10.1007/978-1-4899-2397-4_6
关键词: Stereochemistry 、 Dopamine receptor D1 、 Acetylcholine 、 Receptor 、 Dopamine 、 Adrenergic Agent 、 Chemistry 、 Dopaminergic 、 Dopamine receptor D2 、 Dopamine receptor D3
摘要: Dopamine (DA) 1 is an achiral molecule and thus presents a case akin to those of acetylcholine histamine discussed in later chapters which pair pharmacophores are separated by bimethylene unit. Its receptors, nevertheless, display marked degrees stereoselectivity toward chiral dopaminergic ligands both agonist antagonist character as reviewed Cannon(1) Danish group,(2) respectively, briefly Baindur Neumeyer.(3) The dopamine system has much common with that adrenergic agents, including features vivo synthesis, metabolism, uptake release, interaction adenylate cyclase.
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