Biomarker-Driven Therapy in the Neoadjuvant Treatment of Colorectal Liver Metastases
作者： Jason E. Faris , David P. Ryan
DOI: 10.1007/S11888-012-0123-8
关键词: Colorectal cancer 、 Medicine 、 Circulating tumor cell 、 Oncology 、 Cetuximab 、 Bevacizumab 、 Biomarker (medicine) 、 KRAS 、 Neoadjuvant treatment 、 Internal medicine 、 Colorectal surgery
摘要: The use of neoadjuvant strategies for patients with hepatic-limited metastatic colorectal cancer has demonstrated promise improving the outcomes these patients. However, potential toxicities this strategy, along concern missing a critical window resectability raise clinicians and Although currently few biomarkers are available colon overall, genetic, pathologic, imaging-based to provide prognostic predictive information in setting may allow individualized treatment decisions that improve outcomes.
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Robin K. Kelley, Grace Wang, Alan P. Venook, Biomarker Use in Colorectal Cancer Therapy Journal of The National Comprehensive Cancer Network. ,vol. 9, pp. 1293- 1302 ,(2011) , 10.6004/JNCCN.2011.0105
C Marcus, B Tan, David C Linehan, William G Hawkins, Barry A Siegel, Steven M Strasberg, Chemotherapy-Induced Normalization of FDG Uptake by Colorectal Liver Metastases Does Not Usually Indicate Complete Pathologic Response Journal of Gastrointestinal Surgery. ,vol. 11, pp. 1112- 1119 ,(2007) , 10.1007/S11605-007-0218-8
F. A. Vlems, J. H. S. Diepstra, C. J. A. Punt, M. J. L. Ligtenberg, I. M. H. A. Cornelissen, J. H. J. M. van Krieken, T. Wobbes, G. N. P. van Muijen, T. J. M. Ruers, Detection of disseminated tumour cells in blood and bone marrow samples of patients undergoing hepatic resection for metastasis of colorectal cancer. British Journal of Surgery. ,vol. 90, pp. 989- 995 ,(2003) , 10.1002/BJS.4161
Eddie K. Abdalla, René Adam, Anton J. Bilchik, Daniel Jaeck, Jean-Nicolas Vauthey, David Mahvi, Improving Resectability of Hepatic Colorectal Metastases: Expert Consensus Statement Annals of Surgical Oncology. ,vol. 13, pp. 1271- 1280 ,(2006) , 10.1245/S10434-006-9045-5
Hiroshi Nakano, Elie Oussoultzoglou, Edoardo Rosso, Selenia Casnedi, Marie-Pierre Chenard-Neu, Patrick Dufour, Philippe Bachellier, Daniel Jaeck, Sinusoidal injury increases morbidity after major hepatectomy in patients with colorectal liver metastases receiving preoperative chemotherapy. Annals of Surgery. ,vol. 247, pp. 118- 124 ,(2008) , 10.1097/SLA.0B013E31815774DE
David J. Gallagher, Junting Zheng, Marinela Capanu, Dana Haviland, Philip Paty, Robert P. Dematteo, Michael D’Angelica, Yuman Fong, William R. Jarnagin, Peter J. Allen, Nancy Kemeny, Response to Neoadjuvant Chemotherapy Does Not Predict Overall Survival for Patients With Synchronous Colorectal Hepatic Metastases Annals of Surgical Oncology. ,vol. 16, pp. 1844- 1851 ,(2009) , 10.1245/S10434-009-0348-1
T Yokota, T Ura, N Shibata, D Takahari, K Shitara, M Nomura, C Kondo, A Mizota, S Utsunomiya, K Muro, Y Yatabe, BRAF mutation is a powerful prognostic factor in advanced and recurrent colorectal cancer British Journal of Cancer. ,vol. 104, pp. 856- 862 ,(2011) , 10.1038/BJC.2011.19
Shaheen Zakaria, John H. Donohue, Florencia G. Que, Michael B. Farnell, Cathy D. Schleck, Duane M. Ilstrup, David M. Nagorney, Hepatic Resection for Colorectal Metastases: Value for Risk Scoring Systems? Annals of Surgery. ,vol. 246, pp. 183- 191 ,(2007) , 10.1097/SLA.0B013E3180603039
Ulf P. Neumann, Armin Thelen, Christoph Röcken, Daniel Seehofer, Marcus Bahra, Hanno Riess, Sven Jonas, Maximilian Schmeding, Johann Pratschke, Roberta Bova, Peter Neuhaus, Nonresponse to pre-operative chemotherapy does not preclude long-term survival after liver resection in patients with colorectal liver metastases. Surgery. ,vol. 146, pp. 52- 59 ,(2009) , 10.1016/J.SURG.2009.02.004
F Jeroen Vogelaar, Wilma E Mesker, Arjen M Rijken, Gaby W van Pelt, Antonia M van Leeuwen, Hans J Tanke, Rob A Tollenaar, Gerrit J Liefers, Clinical impact of different detection methods for disseminated tumor cells in bone marrow of patients undergoing surgical resection of colorectal liver metastases: a prospective follow-up study. BMC Cancer. ,vol. 10, pp. 153- 153 ,(2010) , 10.1186/1471-2407-10-153