作者: Veronica Carlini , Valeria Calcaterra , Nunzia Decembrino , Laura Rubert , Noemi Pasqua
DOI: 10.1097/MPH.0000000000000563
关键词: Antifungal 、 Overall survival 、 Medicine 、 Appendicitis 、 General surgery 、 Increased risk 、 Laparoscopy 、 Laparoscopic surgery 、 Surgery 、 Gold standard
摘要: In leukemic patients, appendectomy must be approached with caution because of the increased risk complications. Fungal appendicitis is rare and only a few cases have been described in literature, particularly immunocompromised individuals whom this infection can fatal. We present 2 pediatric patients acute myeloid leukemia, who developed during postchemotherapy neutropenic phase, while receiving antifungal prophylaxis. Fever was first sign infection. Laparoscopic performed without postoperative The histologic examination culture analysis showed presence fungal elements; systemic also excluded. children signs peritoneal irritation are not always obvious. histopathologic demonstration elements tissue reaction mandatory for definitive diagnosis. should considered as gold standard procedure to avoid dissemination. Moreover, laparoscopic surgery its inherent mini-invasive surgical advantages may improve overall survival incurring significant