From genome to cellular phenotype--a role for metabolic flux analysis?

作者: Athel Cornish-Bowden , María Luz Cárdenas

DOI: 10.1038/73696

关键词: Metabolic flux analysisCellular phenotypeFlux (metabolism)Cell biologyGenomeBiology

摘要:

参考文章(9)
Stefan Schuster, Thomas Dandekar, Klaus Mauch, Matthias Reuss, David Fell, Recent Developments in Metabolic Pathway Analysis and Their Potential Implications for Biotechnology and Medicine Springer Netherlands. pp. 57- 66 ,(2000) , 10.1007/978-94-011-4072-0_6
Maria Luz Cardenas, Maria L. Cardenas, "Glucokinase": Its Regulation and Role in Liver Metabolism ,(1995)
James E. Bailey, Lessons from metabolic engineering for functional genomics and drug discovery. Nature Biotechnology. ,vol. 17, pp. 616- 618 ,(1999) , 10.1038/10794
Jeffrey Skolnick, Jacquelyn S. Fetrow, Andrzej Kolinski, Structural Genomics and Its Importance for Gene Function Analysis Nature Biotechnology. ,vol. 18, pp. 283- 287 ,(2000) , 10.1038/73723
Stefan Schuster, David A. Fell, Thomas Dandekar, A general definition of metabolic pathways useful for systematic organization and analysis of complex metabolic networks. Nature Biotechnology. ,vol. 18, pp. 326- 332 ,(2000) , 10.1038/73786
A. Cornishbowden, J.H.S. Hofmeyr, M.L. Cardenas, Strategies for Manipulating Metabolic Fluxes in Biotechnology Bioorganic Chemistry. ,vol. 23, pp. 439- 449 ,(1995) , 10.1006/BIOO.1995.1030
J.-M. Claverie, Computational Methods for the Identification of Differential and Coordinated Gene Expression Human Molecular Genetics. ,vol. 8, pp. 1821- 1832 ,(1999) , 10.1093/HMG/8.10.1821
Jean-Michel Claverie, Do we need a huge new centre to annotate the human genome Nature. ,vol. 403, pp. 12- 12 ,(2000) , 10.1038/47343