Is polypharmacy always hazardous? A retrospective cohort analysis using linked electronic health records from primary and secondary care
作者： Rupert A. Payne , Gary A. Abel , Anthony J. Avery , Stewart W. Mercer , Martin O. Roland
DOI: 10.1111/BCP.12292
关键词: Retrospective cohort study 、 Environmental health 、 Polypharmacy 、 Family medicine 、 Hazardous waste 、 Medicine 、 Secondary care 、 Test (assessment) 、 Cohort study 、 Odds ratio 、 Health records
摘要: The effect of age is given in terms an odds ratio for a change 10 years. P values are based on joint test overall variability across categories.
core.ac.uk
sci-hub.se 参考文章(27)
Christopher Beer, Zoë Hyde, Osvaldo P. Almeida, Paul Norman, Graeme J. Hankey, Bu B. Yeap, Leon Flicker, Quality use of medicines and health outcomes among a cohort of community dwelling older men: an observational study British Journal of Clinical Pharmacology. ,vol. 71, pp. 592- 599 ,(2011) , 10.1111/J.1365-2125.2010.03875.X
Janne Moen, Sara Norrgård, Karolina Antonov, J. Lars G. Nilsson, Lena Ring, GPs' perceptions of multiple-medicine use in older patients. Journal of Evaluation in Clinical Practice. ,vol. 16, pp. 69- 75 ,(2010) , 10.1111/J.1365-2753.2008.01116.X
B. Guthrie, K. Payne, P. Alderson, M. E. T. McMurdo, S. W. Mercer, Adapting clinical guidelines to take account of multimorbidity BMJ. ,vol. 345, ,(2012) , 10.1136/BMJ.E6341
Pascale Olivier, Lionel Bertrand, Marie Tubery, Dominique Lauque, Jean-Louis Montastruc, Maryse Lapeyre-Mestre, Hospitalizations because of adverse drug reactions in elderly patients admitted through the emergency department: a prospective survey. Drugs & Aging. ,vol. 26, pp. 475- 482 ,(2009) , 10.2165/00002512-200926060-00004
Aileen B. Dequito, Peter G.M. Mol, Jasperien E. van Doormaal, Rianne J. Zaal, Patricia M.L.A. van den Bemt, Flora M. Haaijer-Ruskamp, Jos G.W. Kosterink, Preventable and non-preventable adverse drug events in hospitalized patients: A prospective chart review in the Netherlands Drug Safety. ,vol. 34, pp. 1089- 1100 ,(2011) , 10.2165/11592030-000000000-00000
B. Guthrie, C. McCowan, P. Davey, C. R. Simpson, T. Dreischulte, K. Barnett, High risk prescribing in primary care patients particularly vulnerable to adverse drug events: cross sectional population database analysis in Scottish general practice BMJ. ,vol. 342, ,(2011) , 10.1136/BMJ.D3514
Mary E. Charlson, Peter Pompei, Kathy L. Ales, C.Ronald MacKenzie, A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation☆ Journal of Chronic Diseases. ,vol. 40, pp. 373- 383 ,(1987) , 10.1016/0021-9681(87)90171-8
C. Pozzi, F. Lapi, G. Mazzaglia, M. Inzitari, M. Boncinelli, P. Geppetti, A. Mugelli, N. Marchionni, M. Di Bari, Is suboptimal prescribing a risk factor for poor health outcomes in community-dwelling elders? The ICARe Dicomano study. Pharmacoepidemiology and Drug Safety. ,vol. 19, pp. 954- 960 ,(2010) , 10.1002/PDS.1997
M Cynthia, CM Boyd, J Darer, C Boult, LP Fried, L Boult, AW Wu, Clinical Practice Guidelines and Quality of Care for Older Patients With Multiple Comorbid Diseases JAMA. ,vol. 294, pp. 716- 724 ,(2005) , 10.1001/JAMA.294.6.716
Kirsten K. Viktil, Hege S. Blix, Tron A. Moger, Aasmund Reikvam, Polypharmacy as commonly defined is an indicator of limited value in the assessment of drug-related problems British Journal of Clinical Pharmacology. ,vol. 63, pp. 187- 195 ,(2007) , 10.1111/J.1365-2125.2006.02744.X